Africa healthcare ecosystem needs to embrace digital and emerging technologies such as Artificial Intelligence to enhance proactive healthcare and preventive public health interventions. Disease Surveillance and Outbreak Prediction: AI algorithms can analyze real-time data from various sources (e.g., social media, medical records, environmental sensors) to detect and predict disease outbreaks earlier and more effectively. This allows for timely interventions, such as targeted vaccinations and resource allocation. 2. Diagnosis and Treatment: AI-powered diagnostic tools can assist healthcare workers in accurately diagnosing diseases, including those with limited access to specialists. AI can also recommend personalized treatment plans based on patient data and medical literature. 3. Drug Discovery and Development: AI can accelerate the process of drug discovery by identifying potential drug candidates and optimizing clinical trial design. This can lead to the development of new and more effective treatments for diseases prevalent in Africa. 4. Health Education and Awareness: